Know-Legal Web Search

Search results

1. Results From The WOW.Com Content Network

2. alpha-2-Macroglobulin - Wikipedia

   en.wikipedia.org/wiki/Alpha-2-Macroglobulin

   alpha-2-Macroglobulin. α2-Macroglobulin ( α2M) or alpha-2-macroglobulin is a large (720 KDa) plasma protein found in the blood. It is mainly produced by the liver, and also locally synthesized by macrophages, fibroblasts, and adrenocortical cells. In humans it is encoded by the A2M gene.

3. Macroglobulin - Wikipedia

   en.wikipedia.org/wiki/Macroglobulin

   Alpha-2 macroglobulin is a notable plasma component with a molecular mass of 820 kDa, about 300 mg/100 ml, and around 10% carbohydrate in 31 glycans. Alpha-2 macroglobulin is a tetrameric protein which means, in essence, that it is predominantly made up of four identical subunits. Alpha-2 macroglobulin's identical subunits contain 1451 amino ...

4. Serum protein electrophoresis - Wikipedia

   en.wikipedia.org/wiki/Serum_protein_electrophoresis

   This zone consists principally of alpha-2 macroglobulin (AMG or A2M) and haptoglobin. There are typically low levels in haemolytic anaemia (haptoglobin is a suicide molecule which binds with free haemoglobin released from red blood cells and these complexes are rapidly removed by phagocytes). Haptoglobin is raised as part of the acute phase ...

5. Acute-phase protein - Wikipedia

   en.wikipedia.org/wiki/Acute-phase_protein

   Alpha 2-macroglobulin and coagulation factors affect coagulation, mainly stimulating it. This pro-coagulant effect may limit infection by trapping pathogens in local blood clots. [ 1 ] Also, some products of the coagulation system can contribute to the innate immune system by their ability to increase vascular permeability and act as ...

6. LRP1 - Wikipedia

   en.wikipedia.org/wiki/LRP1

   LRP1. Low density lipoprotein receptor-related protein 1 ( LRP1 ), also known as alpha-2-macroglobulin receptor ( A2MR ), apolipoprotein E receptor ( APOER) or cluster of differentiation 91 ( CD91 ), is a protein forming a receptor found in the plasma membrane of cells involved in receptor-mediated endocytosis.

7. Low-density lipoprotein receptor-related protein 8 - Wikipedia

   en.wikipedia.org/wiki/Low-density_lipoprotein...

   Studies have shown that a high presence of alpha-2-macroglobulin is present in the neuritic plaques in many Alzheimer patients. Isolation of cDNA encoding proteins associated with Aβ was used to discover alpha-2-macroglobulin. These discoveries may link alpha-2-macroglobulin and its receptors, one of them being ApoER2, to Alzheimer's disease. [17]