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Fenofibrate is a peroxisome proliferator-activated receptor (PPAR) agonist. It activates a type of receptor called the peroxisome proliferator-activated receptor alpha , which is involved in breaking down fat from the diet, especially triglycerides. [2]
Fenofibrate is a fibrate derivative, a prodrug comprising fenofibric acid linked to an isopropyl ester. It lowers lipid levels by activating peroxisome proliferator-activated receptor alpha (PPARα). PPARα activates lipoprotein lipase and reduces apoprotein CIII, which increases lipolysis and elimination of triglyceride-rich particles from plasma.
Clofibrate (trade name Atromid-S) is a lipid-lowering agent used for controlling the high cholesterol and triacylglyceride level in the blood. It belongs to the class of fibrates. It increases lipoprotein lipase activity to promote the conversion of VLDL to LDL, and hence reduce the level of VLDL. It can increase the level of HDL as well.
Fibrates. In pharmacology, the fibrates are a class of amphipathic carboxylic acids and esters. They are derivatives of fibric acid (phenoxyisobutyric acid). They are used for a range of metabolic disorders, mainly hypercholesterolemia (high cholesterol ), and are therefore hypolipidemic agents .
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Versatile was the first company to mass-produce articulated four-wheel-drive tractors, starting in 1966 with the D100 and G100 four-wheel drives. Those ground-breaking tractors were primitive by modern standards, with a 6-cylinder diesel or 8-cylinder gas engine producing 100 horsepower. 1966 models sold for less than CA$10,000.
A Canadian Locomotive Company Baldwin DRS-4-4-1000 in Canadian Pacific Railway livery. The Canadian Locomotive Company, commonly referred to as CLC, was a Canadian manufacturer of railway locomotives located in Kingston, Ontario. Its works were located on the south side of Ontario Street between William and Gore streets on Kingston's waterfront.
S. Savage Arms. Categories: Defence companies of Canada. Firearm manufacturers by country. Manufacturing companies of Canada.
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