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The drug was pure hydrocodone in small 5 and 10 mg tablets, physically similar to the Dilaudid tablets. It is no longer manufactured by Knoll in Germany, nor is a generic available. Hydrocodone was never as common in Europe as it is in North America—dihydrocodeine is used for its spectrum of indications.
Sildenafil and other PDE5 inhibitors are used off-label to alleviate vasospasm and treat severe ischemia and ulcers in fingers and toes for people with secondary Raynaud's phenomenon; [9] [21] these drugs have moderate efficacy for reducing the frequency and duration of vasospastic episodes. [9]
The atypical antipsychotics (AAP), also known as second generation antipsychotics (SGAs) and serotonin–dopamine antagonists (SDAs), [1] [2] are a group of antipsychotic drugs (antipsychotic drugs in general are also known as tranquilizers and neuroleptics, although the latter is usually reserved for the typical antipsychotics) largely introduced after the 1970s and used to treat psychiatric ...
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In 1992, the company bought up the Western Canadian chain Pinder's Drugs, and followed this in 1995, with a chain of 24 Bi-Rite Drug Stores based in western Canada. Also in 1995, Shoppers Drug Mart acquired 135 Big V Drugstores. In 1996, the first Shoppers Home Health Care store opened. When Koffler retired in 1986, he sold the chain to Imasco ...
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