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Cancer is caused by genetic changes leading to uncontrolled cell growth and tumor formation. The basic cause of sporadic (non-familial) cancers is DNA damage and genomic instability. [ 1][ 2] A minority of cancers are due to inherited genetic mutations. [ 3] Most cancers are related to environmental, lifestyle, or behavioral exposures. [ 4]
Signs and symptoms are not mutually exclusive, for example a subjective feeling of fever can be noted as sign by using a thermometer that registers a high reading. [7] Because many symptoms of cancer are gradual in onset and general in nature, cancer screening (also called cancer surveillance) is a key public health priority. This may include ...
Deaths. 10 million annually (2019) [ 6 ] Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. [ 2 ][ 7 ] These contrast with benign tumors, which do not spread. [ 7 ]
The following is a list of the causes of human deaths worldwide for different years arranged by their associated mortality rates. In 2002, there were about 57 million deaths . In 2005, according to the World Health Organization (WHO) using the International Classification of Diseases (ICD), about 58 million people died. [ 1 ]
Lung cancer. Lung cancer, also known as lung carcinoma, is a malignant tumor that begins in the lung. Lung cancer is caused by genetic damage to the DNA of cells in the airways, often caused by cigarette smoking or inhaling damaging chemicals. Damaged airway cells gain the ability to multiply unchecked, causing the growth of a tumor.
A sarcoma is a malignant tumor, a type of cancer that arises from cells of mesenchymal (connective tissue) origin. [1] [2] Connective tissue is a broad term that includes bone, cartilage, muscle, fat, vascular, or other structural tissues, and sarcomas can arise in any of these types of tissues.
The following is a list of cancer types. Cancer is a group of diseases that involve abnormal increases in the number of cells , with the potential to invade or spread to other parts of the body. [ 1 ]
Apoptosis is a form of programmed cell death (cell suicide), the mechanism by which cells are programmed to die in the event they become damaged. Cancer cells are characteristically able to bypass this mechanism. Cells have the ability to 'self-destruct'; a process known as apoptosis. This is required for organisms to grow and develop properly ...