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Synapse Software Corporation (marketed as SynSoft in the UK) was an American software developer and publisher founded in 1981 by Ihor Wolosenko and Ken Grant. [1] Synapse published application software and developer tools and was primarily known for video games. It initially focused on the Atari 8-bit computers, then later developed for the ...
Synapse. Diagram of a chemical synaptic connection. In the nervous system, a synapse [1] is a structure that permits a neuron (or nerve cell) to pass an electrical or chemical signal to another neuron or to the target effector cell. Synapses are essential to the transmission of nervous impulses from one neuron to another, [2] playing a key role ...
The active zone or synaptic active zone is a term first used by Couteaux and Pecot-Dechavassinein in 1970 to define the site of neurotransmitter release. Two neurons make near contact through structures called synapses allowing them to communicate with each other. As shown in the adjacent diagram, a synapse consists of the presynaptic bouton of ...
Methylphenidate. Methylphenidate, sold under the brand names Ritalin ( / ˈrɪtəlɪn / RIT-ə-lin) and Concerta ( / kənˈsɜːrtə / kən-SUR-tə) among others, is a potent central nervous system (CNS) stimulant used medically to treat attention deficit hyperactivity disorder (ADHD) and, to a lesser extent, narcolepsy. It is a primary ...
Synaptogenesis is the formation of synapses between neurons in the nervous system. Although it occurs throughout a healthy person's lifespan, an explosion of synapse formation occurs during early brain development, known as exuberant synaptogenesis. [1] Synaptogenesis is particularly important during an individual's critical period, during ...
Ribbon synapse. The ribbon synapse is a type of neuronal synapse characterized by the presence of an electron-dense structure, the synaptic ribbon, that holds vesicles close to the active zone. [1] It is characterized by a tight vesicle - calcium channel coupling [2] [3] that promotes rapid neurotransmitter release and sustained signal ...
This particular function is considered a scaffold's most basic function. Scaffolds assemble signaling components of a cascade into complexes. This assembly may be able to enhance signaling specificity by preventing unnecessary interactions between signaling proteins, and enhance signaling efficiency by increasing the proximity and effective concentration of components in the scaffold complex.
The trisynaptic circuit or trisynaptic loop is a relay of synaptic transmission in the hippocampus.The trisynaptic circuit is a neural circuit in the hippocampus, which is made up of three major cell groups: granule cells in the dentate gyrus, pyramidal neurons in CA3, and pyramidal neurons in CA1.